- Location-related
(focal, partial syndromes) | Idiopathic - Rolandic epilepsy (benign childhood epilepsy with centroentemporal spikes)
- Occipital epilepsy
|
| Generalized syndromes | Idiopathic - Childhood absalizaence epilepsy
- Juvenile absence epilepsy
Cryptogenic or symptomatic - Infantile spasms (West syndrome)
- Myoclonic astatic epilepsy (Lennox-Gastaut syndrome)
- Epilepsy with myoclonic absences
|
| Syndromes undetermined whether focal or generalized | With both generalized and focal seizures - Neonatal seizures
- Epilepsy with continuous spike-wave during sleep
|
Classification
The International League Against Epilepsy has developed a classification system that combines clinical description with EEG findings. Over 90% of seizure patients may be classified using this system. Using the international classification scheme, seizures may be divided into partial, generalized, or unclassified.
Table 2. Classification of epileptic seizures
| Traditional classification | New nomenclature |
| Focal motor; Jancksonian seizure | 1. Partial seizures (seizures begin locally) 1) Simple (without impairement of consciousness) - With motor symptoms
- With special sensory or somatosensory symptoms
- With autonomic symptoms
- With psychic symptoms
|
| Temporal lobe or psychomotor seizures | 2)Complex (with impairment of consciousness) - Simple partial onset followed by impairment of consciousness - with or without automatisms
- Impaired consciousness at onset-with or without automatisms
3) Secondarily generalized (partial onset evolving to generalized tonic-clonic seizures) |
| Petit mal | 2. Generalized seizures (bilaterally symmetrical and without local onset) |
| Minor motor | |
| Limited grand mal | |
| Grand mal | |
| Drop attacks | 6) Atonic 7) Infantile spasms |
| - | 3. Unclassified seizures 4. Status epilepticus (prolonged partial or generalized seizures without recovery between attacks) |
1) Partial epileptic seizures
Partial seizures begin in one hemisphere of the brain and, unless they become secondarily generalized, result in an asymmetric seizure. Partial seizures may be described as focal or unilateral seizures and may be subdivided into simple and complex. Partial seizure manifest as alterations in motor functions, sensory or somatosensory symptoms, or autonomic symptoms. If there is no impairment of consciousness, the seizures are classified as simple partial. If there is impairment of consciousness, the seizures are described as complex partial. With complex partial seizures, aberration of behavior (automatisms) may occur. Patients may exhibit inappropriate behavior like lip smacking, tearing of clothing and aimless wandering. Often there is postictal period. Complex partial seizures are more likely to progress to a secondarily generalized seizure.
Table 3. Partial epileptic seizures
| Simple partial seizures (focal) | Complex partial seizures |
| Consciousness | Unaffected | Impaired |
| Age group | Any age | Any age |
| Duration | Seconds-minutes | Minutes |
| Symptoms | Depends upon focus localization ; no postictal confusion | Depends upon focus localization ; postictal confusion |
| Ictal EEG | Contralateral epileptiform discharges ; in many instances no ictal abnormalities (in scalp recording) | Unilateral or bilateral epileptiform discharges, diffuse or focal |
| Special features | An aura is simple partial seizure ! | - |
Table 4. Secondarily generalized seizures
| Initial symptoms | Depends - seizure type (simple/complex partial)
- localization of epileptic focus
|
| Subsequent symptoms | Generalized tonic-clonic convulsion |
2) Generalized epileptic seizures
Generalized tonic-clonic seizures are the most common form of epilepsy. It is characterized by the patients losing consciousness and falling at the onset of the seizure. Tonic muscle spasms (rigid posturing of the limbs or torso) occur and may be accompanied by a cry which results from air being moved out of the larynx. Following the tonic phase, there is a period of generalized clonic movements. After the clonic phase, the patients returns to consciousness, but may remain lethargic and confused for varying periods of time.
¨ç Absence seizure
Absence seizure consists of episodes of brief loss of consciousness. Eyelid fluttering, small chewing movements or mild shaking of the hands may be exhibited. The EEG during the seizure has a characteristic 2 to 4 cycles spike and slow wave complex. The patient regain awareness quickly and there is no postictal state. Complex absence seizure may be accompanied by muscle twitching, myoclonic jerking or autonomic manifestations. The patients do not fall as with tonic-clonic seizures.
¨è Tonic-clonic seizures
Tonic-clonic seizures are what many people think as epilepsy. Although they may be preceded by premonitory symptoms known as aura, the majority of patients lose consciousness without warning. The seizure results in a sudden sharp tonic contraction of muscles followed by a period of rigidity. During this period the patient may fall and be injured. During the seizure the patient may cry or moan, lose sphincter control, bite his or her tongue, or develop cyanosis. After the seizure the patient may be unconscious for a variable time, and frequently goes into a deep sleep. Tonic and clonic seizures may occur separately.
¨é Myoclonic
Brief shock-like muscular contractions of the face, trunk, and extremities are known as myoclonic jerks. They may be isolated events or rapidly receptive.
¨ê Atonic
A sudden loss of muscle tone is known as an atonic seizure. This may be described as a head drop, the dropping of a limb, or a slumping to ground.
3) Unclassified seizures
Unclassified seizures include all seizures that cannot be classified because of inadequate or incomplete data.
Table 5. Generalized epileptic seizures
| Absences | Myoclonic seizures | Atonic seizures | Genenalized tonic-clonic seizure |
| Age group | Children and juveniles | Children and juveniles | Infants and children | Any age |
| Duration | Few-30 seconds | 1-5 seconds | Few seconds | 1-3 minutes |
| Symptoms | Sudden loss of consciousness accompanied by staring and blinking; immediate regain of consciousness | Brief jerks in arms or legs | Sudden loss of muscle tone causing severe head injuries (fall) | Initial cry (sometimes); loss of muscle tone; respiratory arrest; cyanosis; tonic convulsions; clonic convulsions; relaxation followed by deep sleep |
| Ictal EEG | Bilateral regular 3 (2-4) Hz spike-waves | Polyspike-waves, spike-waves, or sharp and slow waves | Polyspike-waves, flattening, or low-voltage fast activity | Often obscured by muscle artifacts |
| Special features | Long absence with automatism, lip smacking, chewing, fiddling, fumbling | Often occur in series | - | Possible tongue biting and urinary incontinence |